Everactive is a deep technology company headquartered in Charlottesville, Virginia that creates groundbreaking wireless Ambient IoT devices powered by ultra-low-power circuit technology. The company's origins trace back to pioneering ultra-low-power circuit research conducted by its co-founders at the University of Virginia.

Laser Thermal (also known as Laser Thermal Analysis) is a Charlottesville, Virginia-based precision instrumentation company founded from academic research. It provides advanced thermal property measurement tools for semiconductors, power electronics, and thermal management applications. In 2023, the company announced a $2.9 million investment to expand R&D capacity in Charlottesville.

QC82 is a quantum computing company developing room-temperature, integrated photonic chips for fault-tolerant quantum computing. The company builds infrastructure for quantum computing using proprietary photon detection technology, targeting large-scale simulations in chemistry and materials science.

ReVolt Energy is a solar panel end-of-life management company that recovers and recycles solar infrastructure across the United Kingdom and the United States. The company has developed advanced technology to recycle solar panels at scale using photonics and robotics. ReVolt Energy has collaborated with the University of Virginia's Solutions Lab to explore applications of its recycling technology.

VLNComm is a technology company based in Charlottesville, Virginia that develops Visible Light Communication (LiFi) technology, using LED bulbs and optical energy to provide simultaneous lighting and high-speed wireless data transmission for indoor networking applications.