Biotech venture creation firm founded by former Millennium Pharmaceuticals leadership. Builds companies from concept. Focus: genomics, protein degradation, oncology, neuro. Cambridge MA.

Boston multi-stage VC across healthcare and enterprise software. Backed Veracode, Obalon, Freenome. Partners Terry McGuire and Amir Nashat.

GMO — Boston-based value and quantitative asset manager. $50B+ AUM. Known for Jeremy Grantham's contrarian market calls. Long-only and alternatives.

Global PE firm. $94B AUM. 420+ companies across 43 countries. 800 Boylston St Boston. Sectors: business/financial services, consumer, healthcare, industrial, retail, tech.

Biotech-only VC building companies from formation. Kendall Square Cambridge. Co-founded Intellia, Translate Bio (acq Sanofi), Horizon (acq Amgen). Partners Bruce Booth and Jean-François Formela.

Investment management and advisory for institutional investors. $500B+ advised. Founded 1973. Focus: private equity, VC, hedge funds, real assets. HQ Boston.

Biotech venture creation firm — invents and builds platform companies from scratch. Founded Moderna. 100+ companies, $100B+ aggregate value. CEO/Founder Noubar Afeyan (MIT PhD, McGill undergrad).

Boston-based alternative investment manager. Multi-strategy alternatives for institutional investors.

Non-profit strategic investment arm of the US intelligence community (CIA/IC). CEO: Steve Bowsher (since Dec 2023). 200+ portfolio companies. Singapore office opened Dec 2023. Two parallel tracks — Technology and Venture — with separate reporting lines but shared deal collaboration: the tech track identifies and evaluates technologies; the venture track manages investments and portfolio.

Mass General Brigham Ventures is the venture investment arm of Mass General Brigham, the Boston-based academic health system affiliated with Harvard Medical School. The team combines investment acumen with scientific expertise to support early-stage healthcare companies advancing breakthroughs in medicine and science.

Spark Capital is a venture capital firm that invests in ambitious entrepreneurs and innovative companies, emphasizing culture, independence, and long-term impact.

Growth equity for founder-owned software, internet and consumer companies. $1.1B AUM. 30+ investments in US and Canada. Typical check $10M-$20M.