Tuskegee University is a higher education institution that offers over 60 undergraduate, graduate, and online academic programs across multiple colleges and schools. The university also operates a veterinary teaching hospital and maintains ROTC programs in conjunction with the Air Force, Army, and Navy.

J.F. Drake State Community and Technical College is a historically Black community college in Huntsville, Alabama, founded in 1961 as Huntsville State Vocational Technical College, renamed in 1966 for Joseph Fanning Drake.

Samford University is a private Christian university in Homewood, Alabama.

Alabama A&M University is a public historically Black university located in Huntsville, Alabama that offers undergraduate and graduate degree programs across various disciplines. The university serves a student body focused on academic achievement, campus engagement, and community service within its residential college environment.

Alabama State University is a public higher education institution that offers undergraduate and graduate programs to students. The university hosts campus events, research programs, and athletic activities for its student body and community.

Public research university with a major aerospace and mechanical engineering program that feeds Huntsville's Redstone Arsenal/Cummings Research Park aerospace workforce.

Bishop State Community College is a public two-year community college (an HBCU) in Mobile, Alabama offering transfer, career/technical, and health science programs.

Concordia College Alabama was a historically Black college in Selma, Alabama, founded in 1922 by the Lutheran Church-Missouri Synod and Dr. Rosa J. Young. It closed permanently after its final graduating class in April 2018.

Gadsden State Community College is a historically Black community college in Gadsden, Alabama, founded in 1960 as the Gadsden Vocational Trade School by Eugene N. Prater in response to Black veterans being denied admission to the all-white Alabama School of Trades. Designated an HBCU by the US Department of Education in 1997.

Jackson State University is a public historically Black university that offers undergraduate and graduate degree programs across five colleges: Business, Education and Human Development, Health Sciences, Liberal Arts, and Science, Engineering, and Technology. The university provides fully integrated learning that combines classroom instruction with laboratory work, community engagement, and research opportunities.

Jacksonville State University is a public university offering more than 110 academic programs across five colleges, including arts and sciences, business, education, health professions, and social and behavioral sciences, along with graduate studies. The university serves approximately 10,000 students and offers both on-campus and online degree options.

Lawson State Community College is a community college with two campuses in Bessemer and Birmingham, Alabama that offers approximately 200 programs including degrees, certificates, and skills training in career technical fields, college transfer pathways, business and information technologies, and health professions. The college provides academic support, student services, and career support to help students enter the workforce or transfer to four-year institutions.

Miles College is a historically black college and university (HBCU) that offers undergraduate and graduate degree programs across 30 majors, along with online education options. The institution provides academic programs, athletics, and student organizations while maintaining a 17:1 student-to-teacher ratio and awarding scholarships and grants to 97% of its students.

Shelton State Community College is a two-year historically Black community college in Tuscaloosa, Alabama, one of six HBCU community colleges in the state.

Talladega College is a historically Black university (HBCU) that offers undergraduate and graduate degree programs in liberal arts, STEM, business, humanities, and education. The institution serves approximately 900 students and is ranked nationally for social mobility, with 80% of graduates pursuing advanced degrees.

Trenholm State Community College is a public community college that offers associate degree programs, career and technical training, and workforce development courses across academic, health sciences, and skilled trades disciplines. The college provides programs ranging from general education and business administration to automotive service, nursing, culinary arts, and specialized certifications in areas such as welding, electrical work, and medical assisting.

Troy University is a public university based in Troy, Alabama, with multiple campuses statewide.