Danfoss Power Solutions operates a major mobile-hydraulics manufacturing and Americas Application Development Center at 2800 E 13th St in Ames, Iowa, employing 1,000+ people across three shifts and ranking as Story County's largest private employer.

Research and innovation park in Ames hosting a Collins Aerospace office alongside other tech and agbio tenants.

Renewable Energy Group, Inc. (Nasdaq: REGI, regi.com) was a biodiesel and renewable-fuels producer headquartered in Ames, Iowa operating 12 biorefineries; acquired by Chevron in 2022 and now operates as Chevron Renewable Energy Group. Distinct from Aster Renewable Energy, a KKR-backed Asia-Pacific utility infrastructure platform.