Xavier University of Louisiana is a private, coeducational liberal arts college and the only historically Black Roman Catholic institution of higher education in the United States. The university offers over 50 majors in the arts and sciences, along with graduate and pharmacy programs, and is recognized as a national leader in STEM and health sciences education.

Southern University at New Orleans (SUNO) is a Historically Black College and University (HBCU) that offers undergraduate and graduate degree programs across various disciplines, including nursing, social work, and cybersecurity. SUNO serves students through traditional and non-traditional formats, including an Evening and Weekend College for working adults, and operates specialized centers such as the Center for Grief and Trauma Therapy.

Dillard University is Louisiana's oldest historically Black university offering undergraduate and graduate degrees in arts, business, humanities, nursing, STEM, and other fields. The university is the only institution in America with a program in African American material culture and was the first HBCU to offer a bachelor's degree in theater arts.

Private research university in New Orleans — medicine, public health, business.