UPMC Enterprises is the innovation, commercialization, and venture capital arm of UPMC, investing in healthcare and digital health companies.

Draper Triangle Ventures is an early-stage venture capital firm investing in Midwest startups, with $205M raised and deployed across three funds.

Innovation Works is a Pittsburgh-based venture capital and startup accelerator investing in early-stage Pennsylvania companies.

Birchmere Ventures is an early-stage venture capital firm investing across education, healthcare, recruiting, transportation safety, and sports tech.

Black Tech Nation Ventures is an early-stage venture fund backing diverse-led startups.

Magarac Venture Partners is an early-stage venture capital firm based in Pittsburgh, PA that invests between $500,000 and $5 million in seed and Series A rounds, primarily focusing on Midwest-based technology entrepreneurs. The firm targets founders building companies in sectors that leverage the Midwest technology ecosystem, with a commitment to diversity in its portfolio.