Danfoss Power Solutions operates a major mobile-hydraulics manufacturing and Americas Application Development Center at 2800 E 13th St in Ames, Iowa, employing 1,000+ people across three shifts and ranking as Story County's largest private employer.

Farm Bureau-affiliated insurance and financial services company headquartered in West Des Moines.

Research and innovation park in Ames hosting a Collins Aerospace office alongside other tech and agbio tenants.

Athene Holding is a retirement-services and fixed annuity company (subsidiary of Apollo Global Management) whose U.S. corporate headquarters is a 1,200+ employee campus at 7700 Mills Civic Parkway in West Des Moines, Iowa.

Casey's General Stores (Nasdaq: CASY) operates more than 2,900 convenience stores with in-store pizza kitchens across the Midwest, headquartered in Ankeny, Iowa.

Global avionics hub headquartered in Cedar Rapids, the region's largest employer, supporting roughly 7,000 jobs -- flight deck avionics, cabin electronics, and mission communications.

Global agriscience business center in Johnston, Iowa (corporate HQ is Indianapolis) -- seed, crop protection, and digital agriculture.

Property and casualty insurance company headquartered in Des Moines.

Fareway Stores is an employee-owned Midwest grocery chain headquartered in Boone, Iowa, operating more than 130 stores across Iowa and neighboring states.

John Deere's Waterloo Works in Waterloo, Iowa is one of the company's largest manufacturing complexes worldwide, producing row-crop tractors and engines for Deere & Company, whose corporate headquarters is in Moline, Illinois.

Kingland Systems develops enterprise data-management and regulatory-compliance software for financial services, headquartered at 1401 6th Ave S in Clear Lake, Iowa since its 2014 founding, with additional operations in Ames, Iowa.

Kum & Go is a privately held, family-owned convenience store chain founded in 1959 and headquartered in West Des Moines, Iowa, operating several hundred stores across the Midwest.

Nearly 3.9 million square feet of hyperscale data center space in West Des Moines, with more planned, drawn by cheap power and available land.

MidAmerican Energy is an Iowa electric and natural gas utility headquartered in Des Moines, a Berkshire Hathaway Energy subsidiary, and one of the largest owners of wind generation among U.S. regulated utilities.

Nonprofit tech education and entrepreneurship organization in Cedar Rapids's New Bohemia district, runs the Iowa Startup Accelerator.

Oculus VR was a virtual reality technology company founded in 2012 and acquired by Facebook (now Meta Platforms) in 2014. It developed the Oculus Rift headset and related VR hardware and software; the business was rebranded as Meta Reality Labs and its products now ship under the Meta Quest brand.

Pella Corporation is a privately held manufacturer of windows and doors headquartered in Pella, Iowa since its 1925 founding, operating multiple manufacturing plants across the state.

Fortune 500 financial services and insurance company headquartered in Des Moines.

Renewable Energy Group, Inc. (Nasdaq: REGI, regi.com) was a biodiesel and renewable-fuels producer headquartered in Ames, Iowa operating 12 biorefineries; acquired by Chevron in 2022 and now operates as Chevron Renewable Energy Group. Distinct from Aster Renewable Energy, a KKR-backed Asia-Pacific utility infrastructure platform.

World's largest family-owned manufacturer of grain bins and drying equipment, headquartered in Sheffield, Iowa.