LA startup studio and early-stage investor. Co-founder Peter Pham. Built Dollar Shave Club (sold to Unilever $1B), FabFitFun, PlayVS.

LA seed accelerator combining capital with collaborative community. Supports LA entrepreneurs as they build and scale. Founder: Paul Bricault.

$100B+ AUM. Co-founded by Marc Andreessen & Ben Horowitz 2009. Invests seed to growth across AI, bio, consumer, crypto, enterprise, fintech, games, infrastructure, American Dynamism. HQ Menlo Park CA. [2026-06-04, operator-stated: a16z has transitioned toward a PE/crossover model — invests in BOTH private and public companies (registered investment advisor; public-market positions held via the a16z Perennial sub-arm). Public holdings are core a16z activity, not a separate non-venture sidecar.]

Pure-play biotech VC spun out of Avalon Ventures in 2022. $135M Fund I. Managing Partners: Jay Lichter, Sandy Madigan, Tighe Reardon, Sergio Duron. Kevin Kinsella = Emeritus Partner. Incubation model with in-house labs. Notable exits: Nerio Therapeutics ($1.3B, Boehringer Ingelheim 2024), Calporta ($576M Merck).

La Jolla-based seed/early VC. $750M+ invested across 11 funds. Life sciences and tech. Founded by Kevin Kinsella. 125+ companies. Notable: Vertex, Synaptics, Vocera, Onyx Pharma. WSJ top biotech VC. [merged from 817]: San Diego's pioneering life sciences + tech VC. Founded 1983 by Kevin Kinsella. $750M+ deployed. Separate Avalon BioVentures fund ($135M, 2022) exclusively for early-stage biotech. Managing Partners: Jay Lichter, Sandy Madigan, Tighe Reardon. Accelerator model: incubates companies internally before bringing in co-investors. Notable: Erasca, Janux, Synthorx (acq. Sanofi $2.5B), Calporta (acq. Merck), Nerio (acq. Boehringer-Ingelheim $1.3B).

$5.3B AUM. Growth equity and PE. Consumer, financial, health, travel verticals. Co-founder Raj Ganguly. Backed Lambda, Accacia, Carlsmed.

Data-driven co-investor. Uses AI/analytics to make rapid investment decisions (days vs months). Co-invests across all stages and sectors. Most active early-stage VC co-investor in US. Notable: Upstart, Mitek Systems. [merged from 820]: San Diego data-driven VC. Revolutionary model: rapid investment decisions using predictive analytics. Co-invests across multiple sectors and stages. Notable: Acuitas Medical ($85M Series D), Nerio Therapeutics (Avalon syndicate).

Early-stage LA VC. Fund VI investing in frontier tech: space exploration, clean energy, advanced manufacturing. 118 companies, 4 unicorns. Partners: Rick Smith, Brian Garrett, Brett Brewer.

Exclusive life sciences VC since 1985. $2B AUM. Princeton NJ HQ + San Diego office. Pharma, medical devices, diagnostics. Has backed Neurocrine Biosciences across $100M+ in multiple rounds.

SoCal's leading startup tech incubator (originally CommNexus 1998). Free incubation for early-stage startups. SD + Irvine + LA locations. No equity taken. Founded by Mike Krenn. Strong connections to local VC community. [merged from 823]: Southern California's leading startup technology incubator. San Diego flagship. Mentorship, capital access, strategic partnerships. Tech and deep tech focus. Key gateway to San Diego VC community.

Largest VC focused on real estate technology (PropTech). $4B+ AUM. Bridges legacy real estate companies with tech startups. Also manages climate tech and retail funds. HQ LA. CEO/CIO: Brendan Wallace; Co-Founder & Chairman: Brad Greiwe.

LA boutique seed fund. Invests in founders solving systemic problems through data, AI, and automation. Partner: Eva Ho.

Leading agtech and life sciences VC. Global reach: US, Australia, Israel, New Zealand, Canada. Seed to late stage. San Diego + Palo Alto offices. Focus: food security, sustainability, ag innovation. [merged from 822]: San Diego agricultural technology and sustainability VC. Global reach with local roots. Early agtech pioneer. Invests in food security, precision agriculture, biotech for food systems.

Consumer-focused VC combining venture capital with a startup studio. Backs companies transforming how people live, work, and play. Co-founders: Carter Reum and Courtney Reum.

Cross Culture + M Ventures merger. Seed.

$1.65B AUM over 4 funds. Growth-stage enterprise software and AI. HQ Santa Monica. Backed CrowdStrike, KnowBe4, Forter. Hosts The Montgomery Summit annually (~1,000+ attendees). Co-Founder & Managing Partner: Jamie Montgomery.

DMV-active PE firm backing software and tech-enabled services. Active in DC government IT space.